In order to fully implement the spirit of the 19th National Congress of the Communist Party of China, accelerate the construction of an innovation-oriented country, and vigorously promote the innovation-driven development strategy and intellectual property strategy, the National Intellectual Property Administration, according to the provisions of the Evaluation for China Patent Awards , recommended by the department, reviewed by the Chinese Patent Awards Committee, the National Intellectual Property Administration and the World Intellectual Property Organization, 2'-fluorine-4'-substituted nucleoside analogue invented by Professor Junbiao Chang, its preparation method and application (ZL200710137548.0) was given the China Patent Gold Award. This year, there are 1,554 outstanding patents participated in this selection, and finally 20 Chinese Patent Gold Awards were selected (No. 77 [2017] of the National Intellectual Property Administration). This award is a manifestation of its outstanding contribution in promoting technological innovation and economic and social development.