张杏丽

发布者:刘敏发布时间:2023-02-12浏览次数:2866

姓名
张杏丽
职称
讲师
办公电话
15516628809
电子邮箱
zhxl929@126.com;zhangxingli@htu.edu.cn
个人简介

2007.09-2011.07,河南农业大学,环境工程,工学学士

2011.09-2014.07,南开大学,环境科学,理学硕士

2014.09-2018.07,南开大学,环境科学,理学博士

2018.0–至今,betway官方app ,环境学院,讲师(校聘副教授)

张杏丽(1987—),女,博士,硕士生导师。主持国家自然科学基金青年基金1项,国家博士后面上项目1项,参与国家自然基金面上项目3项。在Environmental Science Technology,Environment International,Journal of Hazardous Materials, Science of the Total Environment,Environmental Pollution,《环境科学》等国内外期刊上发表学术论文20余篇,其中第一作者/通讯作者发表SCI论文6篇,中文核心3篇。主要从事环境新型有机污染物及微纳米污染物的生态毒理及人体健康风险评估研究。

研究领域

(1)新型环境污染物(有机污染物,微纳米污染物)在水环境中的转化,生物富集及毒理效应;

(2)多组学联合(转录组学、蛋白组学及代谢组学)技术揭示水生生物对污染物的分子响应机制;

主近期主要开展微塑料的环境老化过程机制及人体健康风险评估,以及环境特征微塑料对水体中典型有机污染物生物富集及生态毒性的影响研究。

主要学术及社会兼职

生态毒理学会会员

担任J. Hazard. Mater.、Sci. Total Environ.等多个期刊的审稿人

主持或参加科研项目情况

近年来主持或参与的主要科研项目:

1. 国家自然科学基金青年科学基金项目(41907349),微塑料对有机磷阻燃剂生物跨代效应的影响及其分子机制研究,2020.01-2022.12,主持;

2. 中国博士后科学基金面上资助(2019M662499),胞外聚合物调控微塑料水环境行为及生物效应的机制研究,2019.12-2022.12,主持;

3. 国家自然科学基金面上项目(21876092),纳米结构对模拟氧化石墨烯产品环境释放与生物效应的调控作用及分子机制研究,2019.01-2022.12,参与;

4. 国家自然科学基金面上项目(21677080),石墨烯纳米材料对典型水生物的代谢毒性及其机理,2017.01-2020.12,参与;

5. 国家自然科学基金青年科学基金项目(21307061),石墨烯在水体中的化学行为转变及其微观机理研究,2014.01-2016.12,参与

学术成果

代表性论文:

1. Zou, W.; Xia, M.L.; Jiang, K.; Cao, Z.G.; Zhang X.L.,* et al. Photo−oxidative degradation mitigated the developmental toxicity of polyamide microplastics to zebrafish larvae by modulating macrophage−triggered proinflammatory responses and apoptosis. Environmental Science & Technology 2020, 13888-13898.

2. Zhang, X.L. et al.Photoaging enhanced the adverse effects of polyamide microplastics on the growth, intestinal health, and lipid absorption in developing zebrafish.Environment International 2022,158, 106922.

3. Zhang, X.L.* et al.Photolytic degradation elevated the toxicity of polylactic acid microplastics to developing zebrafish by triggering mitochondrial dysfunction and apoptosis. Journal of Hazardous Materials 2021, 413,125321.

4. Zhang, X.L. et al. Integrating omics and traditional analyses to profile the synergistic toxicity of graphene oxide and triphenyl phosphate. Environmental Pollution 2020, 263,114473.

5. Zhang, X.L. et al. Molecular mechanisms of developmental toxicity induced by graphene oxide at predicted environmental concentrations. Environmental Science & Technology 2017, 51, 7861-7871.

6. Zhang, X.L. et al. Rice ingestion is a major pathway for human exposure to organophosphate flame retardants (OPFRs) in China. Journal of Hazardous Materials2016, 318, 686-693.

7. Zou, W.; Li, X.; Li, C.; Sun, Y.; Zhang, X.L., et al. Influence of Size and Phase on the Biodegradation, Excretion, and Phytotoxicity Persistence of Single-Layer Molybdenum Disulfide. Environmental Science & Technology 2020, 54, 19, 12295-12306.

8. Zou, W.; Zhou, Q.; Zhang, X.L., et al. Dissolved oxygen and visible light irradiation drive the structural alterations and phytotoxicity mitigation of single-layer molybdenum disulfide. Environmental Science & Technology 2019, 53, 7759−7769

9. Zou, W.; Zhou, Q.; Zhang, X.L., et al. Environmental transformations and phytotoxicity of single layer molybdenum disulfide regulated by human acid. Environmental Science & Technology 2018, 52, 2638−2648.

10. Zou, W.; Zhang, X.L., et al. Graphene oxide nanosheets mitigate the developmental toxicity of TDCIPP in zebrafish via activating the mitochondrial respiratory chain and energy metabolism. Science of the Total Environment 2020, 727, 138486.

11. Zou, W.; Zhou, Q.; Zhang, X.L., et al. Characterization of the effects of trace concentrations of graphene oxide on zebrafish larvae through proteomic and standard methods. Ecotoxicology and Environmental Safety 2018,159, 221–231.

12. Zou, W.; Zhang, X.L., et al. Cellular proliferation and differentiation induced by single-layer molybdenum disulfide and mediation mechanisms of proteins via the Akt-mTOR-p70S6K signaling pathway. Nanotoxicology 2017, 11, 781-793.

13. 张杏丽, 邹威,周启星*.基于代谢组学技术分析磷酸三苯酯诱导斑马鱼胚胎发育毒性的分子机制.生态毒理学报 2019, 3, 79-89.

14. 张杏丽, 邹威,周启星*. 镉-八氯代二苯并呋喃复合污染土壤中紫茉莉对镉的修复能力. 环境科学2015, 8, 3045-3055.

15. 张杏丽, 周启星*. 土壤环境多氯二苯并二噁英/呋喃(PCDD/Fs)污染及其修复研究. 生态学杂志2013, 32,1054-1064.

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