申聪聪

时间:2020-07-19浏览:5512设置


个人简介:

申聪聪,1989出生,河南洛阳人,博士,讲师,

E-mailshencongcong@htu.edu.cn


教育经历:

2008.09—2012.06商丘师范学院 化学 理学学士

2012.09—2015.06中南大学 分析化学 理学硕士

2015.09—2018.11中南大学 分析化学 理学博士



主讲课程:

分析化学、仪器分析、分析化学实验、仪器分析实验、药物化学实验等。


研究领域与方向

纳米新材料的合成,荧光纳米探针的设计及生物成像;

新型电化学生物传感体系的构建,并用于体内特定酶、糖蛋白、循环肿瘤细胞等癌症标志物的检测。


主持的科研项目

1、河南省科技攻关项目:新型循环肿瘤细胞(CTC)电化学传感体系的构建及其在临床早筛液体活检中的应用(10.00万,项目编号:2021023101392020.1-2021.12,在研)

2betway官方app 博士科研启动费支持课题:基于DNA产生电流技术构建电化细胞传感器用于乳腺癌循环肿瘤细胞的检测8.00万,2020.1-2022.12,在研)

3、betway官方app 国家级青年科学基金培育项目(4.00万,在研)

4、湖南省博士研究生科研创新项目:基于上转换纳米颗粒光解药物缓释用于乳腺癌治疗(3.00万,项目编号:CX2016B039),已结题。


代表性成果:

<文章>

[1]Congcong Shen, Shuping Liu, Xiaoqing Li, and Minghui Yang*.Electrochemical Detection of Circulating Tumor Cells Based on DNA Generated Electrochemical Current and Rolling Circle Amplification.Analytical Chemistry, 2019, (91): 11614-11619.(IF=6.042)

[2]Congcong Shen, Ke Zeng, Junjun Luo, Xiaoqing Li, Minghui Yang*, and Avraham Rasooly*. Self-Assembled DNA Generated Electric Current Biosensor for HER2 Analysis [J].Analytical Chemistry, 2017, 89(19): 10264-10269.(IF=6.042)

[3]Congcong Shen, Xiaodong Xia, Shengqiang Hu, Minghui Yang, and Jianxiu Wang. Silver nanoclusters-based fluorescence assay of protein kinase activity and its inhibitors.Analytical Chemistry, 2015, (87): 693-698.(IF=6.042)

[4]Congcong Shen, Xiangzhi Li, Avraham Rasooly, Linyan Guo, Kaina Zhang, Minghui Yang. A Single Electrochemical Biosensor for Detecting the Activity of Both Protein Kinase and Alkaline Phosphatase Based on Phosphate Ions Induced Deposition of Redox Precipitates.Biosensors and Bioelectronics, 2016, (85), 220-225.(IF=7.476)

[5]Congcong Shen#, Juan Su#, Xiangzhi Li, Junjun Luo, Minghui Yang. Electrochemical sensing platform based on Pd-Au bimetallic clusters for non-enzymatic detection of glucose.Sensors and Actuators, B chemical, 2015(209): 695-700.(IF=5.667)

[6]Congcong Shen#, Kaina Zhang#, Nanxing Gao, Shijiong Wei, Guimei Liu, Yuanlin Chai, Minghui Yang*. Dual Modes of Colorimetric and Electrochemical Sensor for Detecting the Activity of Protein Kinase Based on Silver Enhancement Signal Amplification.Microchimica Acta.2016 183:2933–2939(IF=5.705

[7]Congcong Shen#, Shuping Liu#, Xiaoqing Li, Dan Zhao, Minghui Yang*Immunoelectrochemical detection of HER2 with gold nanoparticle-based rolling circle amplification.Microchim Acta. 2018 185:574-581(IF=5.705

[8]申聪聪,阳明辉。蛋白激酶活性及抑制性检测研究进展,化学传感器。2015, 35 (1):49-57

[9] Xiaoqing Li,Congcong Shen, Minghui Yang,*and Avraham Rasooly*, Polycytosine DNA Electric-Current-Generated Immunosensor for Electrochemical Detection of Human Epidermal Growth Factor Receptor 2 (HER2).Analytical Chemistry, 2018, 90(7): 4764-4769.(IF=6.042)

[10] Lanshuang Hu, Shengqiang Hu, Linyan Guo,Congcong Shen, Minghui Yang,*and Avraham Rasooly*. DNA Generated Electric Current Biosensor.Analytical Chemistry, 2017, 89(4): 2547-2552.(IF=6.042)

[11] Yuxin Li,Congcong Shen, Xiaoqing Li, Minghui Yang*, and Chunshen Shao*. Hydroxyapatite nanoparticle based fluorometic determination and imaging of cysteine and homocysteine in living cells.Microchim Acta, 2018, 185(5):271-278.(IF=5.705

[12] Kaina Zhang, Ke Zeng,Congcong Shen, Shiyu Tian, Minghui Yang*, Determination of protein kinase A activity and inhibition by using hydroxyapatite nanoparticles as a fluorescent probe.Microchim Acta, 2018, 185(4):225-232.(IF=5.705

[13] Yuxin Li, Xiaoqing Li, Dan Wang,Congcong Shen, Minghui Yang, Hydroxyaptite nanoparticle based fluorometric turn-on determination of dipicolinic acid, a biomarker of bacterial spores.Microchim Acta, 2018 185: 2978-2982.(IF=5.705

[14] Ke Zeng, Shiyu Tian, Zixiao Wang,Congcong Shen, Junjun Luo, Minghui Yang, You-Nian Liu, An ELISA for the determination of human IgG based on the formation of a colored iron(II) complex and photometric or visual read-out.Microchim Acta, 2017 184: 2791-2796.(IF=5.705

[15] Luo Junjun, Avraham Rasooly,Wang Liqiang, Zeng Ke,Shen Congcong, Minghui Yang. Fluorescent turn-on determination of the activity of peptidases using peptide templated gold nanoclusters.Microchimica Acta,2016,183(2): 605-610.(IF=5.705

[16] Songbai Zhang, Xia Hu, Hongen Geng, Meixin Huang, Yangqing Qiu,Congcong Shen, Shuo Wang, Guangyu Shen, Minghui Yang, A highly sensitive and signal –on electrochemical aptasensor based on restriction endonuclease induced background elimination.Journal of the Electrochemical Society. 2016 163(8): B411-B416.(IF=3.48)

[17] Qingjun Guo, Xiangzhi Li ,Congcong Shen,Song bai Zhang, Haizhi Qi, Ting Li, Minghui Yang. Electrochemical immunoassay for the protein biomarker mucin 1 and for MCF-7 cancer cells based on signal enhancement by silver nanoclusters.Microchim Acta, 2015,182(7-8):1483-1489.(IF=5.705

[18] Miao Zhou, Zhifang Sun,Congcong Shen, Zhengyuan Li, Yi Zhang , Minghui Yang. Application of hydrogel prepared from ferrocene functionalized amino acid in the design of novel electrochemical immunosensing platform.Biosensors and Bioelectronics, 2013, (49): 243-248.(IF=7.476)


<专利>

[1]阳明辉,申聪聪,一种测定蛋白激酶活性的方法和蛋白激酶抑制剂活性的方法,已授权,专利号:ZL 201610058928.4

[2]阳明辉,申聪聪,张凯娜,一种基于比色法或电化学法测定蛋白激酶PKA的活性的方法,已授权,专利号:ZL 2016 1 0552292.9

[3]阳明辉,申聪聪,基于DNA产生电信号及自组装放大信号的电化学适配体传感器测定HER2的方法,已授权,专利号:ZL 2017 1 0091611.5

获奖情况

12016年获得“中南大学拔尖博士校长奖学金”。

22017年获得中南大学优秀硕士学位论文。

32017年获得湖南省优秀硕士学位论文。



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