教育与研究经历：

1997,09- 2001,07betway官方app 化学与环境科学学院化学教育专业理学学士

2001,09 - 2004,07betway官方app 化学与环境科学学院有机化学专业理学硕士

2004,08 -2007,07北京大学药学院，天然产物与仿生药物国家重点实验室，化学生物学专业博士

2009,12-2010,06美国内华达大学医学院，生理学系，NIH访问学者

2011, 12- 2012.12美国Scripps研究所，化学生物学专业博士后

2007,07-至今betway官方app 化学与化工学院副教授，教授
主讲课程：

《化学生物学概论》，《核酸药物化学》，《波谱分析与实验》

研究领域与兴趣：

核酸化学生物学，生物有机化学，高通量化学生物学方法

近年来主持的主要科研项目:

国家自然科学基金项目(21778015):蛋白质ADP-核糖化稳定结构模拟物的设计合成及化学遗传学研究(2018-2021)

国家自然科学基金项目(21172058):基于靶导向合成(TGS)策略新型NAD+类似物的设计合成及活性研究(2012-2015)

河南省科技创新杰出青年支持计划（164100510020：基于人造基因密码的核酸定点标记技术及应用（2016-2018）

河南省高校创新人才支持计划(2012HASTIT10):新型核苷酸类细胞信号分子的设计合成及活性研究(2012-2014)

国家自然科学基金项目(20802017):基于click化学的新型简单结构cADPR类似物的设计合成及活性研究(2009-2011)

代表性论文：

1. Feldman, Aaron W.;† Dien, Vivian T.;† Karadeema, Rebekah J.; Fischer, Emil C.; You, Yanbo; Chen, Jason S; Li, Lingjun.*; Romesberg, Floyd. E.* Optimization of Replication, Transcription, and Translation in a Semi-Synthetic Organism.J. Am. Chem. Soc.2019, 141 (27), 10644-10653. (IF = 14.357)

2. Li, Lingjun; Degardin, Melissa; Lavergne, Thomas; Malyshev, Denis A.; Dhami, Kirandeep; Ordoukhanian, Phillip; Romesberg, Floyd E.* Natural-like Replication of an Unnatural Base Pair for the Expansion of the Genetic Alphabet and Biotechnology Applications.J. Am. Chem. Soc.2014, 136 (3), 826-829. (IF = 14.357)

3. Zhang, Yorke; Lamb, Brian M; Feldman, Aaron W; Zhou, Anne Xiaozhou; Lavergne, Thomas; Li, Lingjun; Romesberg, Floyd E*. A semisynthetic organism engineered for the stable expansion of the genetic alphabet.Proc. Natl. Acad. Sci. U S A2017, 114 (6), 1317-1322. (IF = 9.674)

4. Zhu, Anlian; Li, Lingjun;* Zhang, Chi; Shen Yutan; Tang, Mingjie, Bai, Lili; Du, Chunyan; Zhang, Suojiang; Wang, Jianji* An Integrated High-throughput Strategy Enables the Discovery of Multifunctional Ionic Liquids for Sustainable Chemical Processes.Green Chem.2019, 21(2), 307-313. (IF = 9.405)

5. Zhu, Anlian;* Xing, Xiaofang; Wang, Shilei; Yuan, Donghe; Zhu, Gongmin; Geng, Mingwei; Guo, Yuanyang; Zhang, Guisheng; Li, Lingjun* Multi-component Syntheses of Diverse 5-Fluoroalkyl-1,2,3-triazoles Facilitated by Air Oxidation and Copper Catalysis.Green Chem.2019, 21 (12), 3407- 3412 (IF = 9.405)

6. Li, Lingjun*; Ding, Shengqiang; Yang, Yanping; Zhu, Anlian; Fan, Xincui; Cui, Mengchao*; Chen, Changpo; Zhang, Guisheng*. Multicomponent Aqueous Synthesis of Iodo-1,2,3-triazoles: Single-Step Models for Dual Modification of Free Peptide and Radioactive Iodo Labeling.Chemistry-A European Journal2017, 23 (5), 1166-1172. (IF = 5.160)

7. Li, Lingjun;* Huang, Shenlong; Shang, Tongpeng, Zhang, Bo; Guo, Yuanyang; Zhu, Gongming; Zhou, Demin;* Zhang, Guisheng;* Zhu, Anlian; Zhang Lihe. Medium Rings Bearing Bitriazolyls: Easily Accessible Structures with Superior Performance as Cu Catalyst Ligands.J. Org. Chem. 2018, 83(21), 13166−13177. (IF = 4.85)

8. Lavergne, T.; Lamichhane, R.; Malyshev, D. A.; Li, Zhengtao Li; Li, Lingjun; Sperling, Edit ; Williamson, James R.; Millar, David P.; Romesberg. Floyd E. FRET Characterization of Complex Conformational Changes in a Large 16S Ribosomal RNA Fragment Site-Specifically Labeled Using Unnatural Base Pairs.ACS Chem. Biol., 2016. 11(5), 1347−1353. (IF = 5.331)