苏莉
个人简介：
苏莉，博士，副教授，硕士生导师
电话：15837369659
E-mail：suli@htu.edu.cn
教育经历：
2004.9-2008.6信阳师范学院化学化工学院理学学士
工作经历：
2013.7-至今betway官方app化学化工学院 讲师、副教授
研究领域与兴趣：
1、纳米酶材料的设计合成
2、生化分析、生物传感与生物成像
3、活性氧调控与疾病治疗
近年来主持的主要科研项目:
1、国家自然科学基金:酞菁类MOFs材料模拟酶的设计合成及其在可视化检测中的应用研究,项目编号:21405034,2015.1-2017.12
2、河南省科技攻关项目:新型金属有机骨架纳米酶传感体系的构建及其在有机磷农药残留检测中的应用,项目编号:192102210041,2019.1-2020.12
3、betway官方app 国家级科研项目培育基金:多色荧光碳基纳米酶生物传感器的构建及活细胞内过氧化氢检测与成像分析,项目编号:2019PL12,2019.1-2021.12
4、河南省高等学校重点科研项目:磁性纳米材料模拟酶的催化机理及其应用研究,项目编号:14B150020, 2014.1-2016.12
代表性论文：
[10]Li Su*, Sainan Qin, Zhongjian Xie, Liang Wang*, Karim Khan, Ayesha Khan Tareen, Defa Li*, Han Zhang*, Multi-enzyme activity nanozymes for biosensing and disease treatment.Coordination Chemistry Reviews,2022,473, 214784.
[8]Li Su*, Yexi Cai, Liang Wang, Wenpei Dong, Guojiang Mao, Ye Li, Mingsheng Zhao, Yanhua Ma, Hua Zhang*. Hemin@carbon dot hybrid nanozymes with peroxidase mimicking properties for dual (colorimetric and fluorometric) sensing of hydrogen peroxide, glucose and xanthine.Microchimica Acta, 2020, 187, 132.
[7]Li Su*, Xinai Yu, YuqiMiao, Guojiang Mao, Wenpei Dong, Suling Feng, Siman Liu, Like Yang, Kaige Zhang, Hua Zhang*. Alkaline-promoted regulation of the peroxidase-like activity of Ni/Co LDHs and development bioassays.Talanta,2019, 197, 181-188.
[6]Li Su*, Xinai Yu, Yexi Cai, Puhua Kang, Wenjie Qin, Wenpei Dong, Guojiang Mao, Suling Feng*. Evaluation of fluorogenic substrates for Ni/Co LDHs peroxidase mimic and application for determination of inhibitory effects of antioxidant.Analytica Chimica Acta,2017, 987, 98-104.
[5]Li Su*, Wenpei Dong, Chengke Wu, Yijun Gong, Yan Zhang, Ling Li, Guojiang Mao, Suling Feng*. The peroxidase and oxidase-like activity of NiCo2O4mesoporous spheres: Mechanistic understanding and colorimetric biosensing.Analytica Chimica Acta,2017, 951,124-132.
[4]Li Su*, Xinai Yu, Wenjie Qin, Wenpei Dong, Chengke Wu, Yan Zhang, Guojiang Mao and Suling Feng*. One-step analysis of glucose and acetylcholine in water based on the intrinsic peroxidase-like activity of Ni/Co LDHs microspheres.Journal of Materials Chemistry B,2017, 5, 116-122.
[3]Li Su, Wenjie Qin, Huige Zhang, Zia Ur Rahman, Cuiling Ren, Sudai Ma, Xingguo Chen*. The peroxidase/catalase-like activities of MFe2O4(M=Mg, Ni, Cu) MNPs and their application in colorimetric biosensing of glucose.Biosensors and Bioelectronics,2015, 63, 384-391.（截止2020年7月被引109次）
[2]Li Su, Jie Feng, Ximin Zhou, Cuiling Ren, Honghong Li, Xingguo Chen*. Colorimetric detection of urine glucose based ZnFe2O4magnetic nanoparticles.Analytical Chemistry,2012, 84, 5753-5758.（截止2020年7月被引309次）
[1]Li Su, Lina Li, Yanwei Li, Xiaoyun Zhang*, Xiaoyan Huang, Honglin Zhai. Simple and accurate approaches to predict the activity of benzothiadiazine derivatives as HCV inhibitors.Medicinal Chemistry Research,2012, 21:2079–2096
合作论文:
[1] Mao G-J, Gao G-Q, Liang Z-Z, Wang Y-Y,Su L, Wang Z-X, Zhang H, Ma Q-J, Zhang G. A mitochondria-targetable two-photon fluorescent probe with a far-red to near-infrared emission for sensing hypochlorite in biosystems. Analytica Chimica Acta, 2019, 1081:184-192.
[2] Mao G-J, Liang Z-Z, Bi J, Zhang H, Meng H-M,Su L, Gong Y-J, Feng S, Zhang G. A near-infrared fluorescent probe based on photostable Si-rhodamine for imaging hypochlorous acid during lysosome-involved inflammatory response. Analytica Chimica Acta, 2019, 1048:143-153.
[3] Mao G-J, Liang Z-Z, Gao G-Q, Wang Y-Y, Guo X-Y,Su L, Zhang H, Ma Q-J, Zhang G. A photostable Si-rhodamine-based near-infrared fluorescent probe for monitoring lysosomal pH during heat stroke. Analytica Chimica Acta, 2019, 1092:117-125.
[4] Gong Y-J, Zhang X-B, Mao G-J,Su L, Meng H-M, Tan W, Feng S, Zhang G. A unique approach toward near-infrared fluorescent probes for bioimaging with remarkably enhanced contrast. Chem Sci, 2016, 7: 2275-2285.
[5] Duan J, Yu J, Feng S,Su L. A rapid microwave synthesis of nitrogen-sulfur co-doped carbon nanodots as highly sensitive and selective fluorescence probes for ascorbic acid. Talanta, 2016, 153:332-339.
[6] Cui Y, Gong Y-J,Su L, Wu C-K, Pang S-B, Feng S-L. Spectroscopy studies of sandwich-type complex of silver(I) co-ordinated to nuclear fast red and adenine and its analytical applications. Chemical Papers, 2015, 69: 510-517.
[7] Wu C, An X, Gao S,Su L. Self-assembly of cuprous oxide nanoparticles supported on reduced graphene oxide and their enhanced performance for catalytic reduction of nitrophenols. Rsc Advances, 2015, 5: 71259-71267.
[8] Qin W,Su L, Yang C, Ma Y, Zhang H, Chen X. Colorimetric Detection of Sulfite in Foods by a TMB-O2-Co3O4Nanoparticles Detection System. Journal of Agricultural and Food Chemistry, 2014, 62: 5827-5834.
[9] Feng J,Su L, Ma Y, Ren C, Guo Q, Chen X. CuFe2O4magnetic nanoparticles: A simple and efficient catalyst for the reduction of nitrophenol. Chemical Engineering Journal, 2013, 221:16-24.
[10] Zhou X, Lu W,Su L, Dong Y, Li Q, Chen X. The binding affinity of amino acid-protein: hydroxyproline binding site I on human serum albumin. Organic & Biomolecular Chemistry, 2012, 10: 8314-8321.
[11] Zhou X-M, Lue W-J,Su L, Shan Z-J, Chen X-G. Binding of Phthalate Plasticizers to Human Serum Albumin in Vitro: A Multispectroscopic Approach and Molecular Modeling. Journal of Agricultural and Food Chemistry, 2012, 60: 1135-1145.
[12] Ji C, Li Y,Su L, Zhang X, Chen X. Quantitative structure-retention relationships for mycotoxins and fungal metabolites in LC-MS/MS. Journal of Separation Science, 2009, 32: 3967-3979.
授权专利：
1、苏莉，于心爱，张艳，等.一种规模化制备碳混合过渡金属氧化物多孔微球的方法，ZL201510819333.1
2、苏莉，于心爱，董文佩，等.一种规模化制备过渡金属氧化物多孔微球的方法，ZL201510819790.0
3、苏莉，蔡晔茜，毛国江，等. 基于比色荧光双通道的纳米模拟酶及其在分析检测中应用. ZL201711433046.2
获得荣誉与奖励：
1、2018年6月 指导学生获得“2018年betway官方app 优秀硕士毕业论文”。
2、2018年9月 获“betway官方app 优秀教师”。
3、河南省教育厅科技成果奖优秀科技论文(Analytica Chimica Acta,2017, 951,124-132),一等奖, 2020.
4、河南省教育厅科技成果奖优秀科技论文(Journal of Materials Chemistry B,2017, 5, 116-122.), 二等奖, 2020.
5、2021年10月获得河南省教育系统教学技能技能竞赛三等奖。
