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王东超，男，中共党员，博士，副教授，硕士生导师，河南省高校科技创新团队带头人，河南省高校青年骨干教师。 1997-2001年，betway官方app ，学士 2005-2008年，betway官方app ，硕士 2013-2016年，betway官方app ，博士 电话：0373-3329276 Email:wangdc@htu.edu.cn |
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主讲课程： 主持项目： 1.国家自然科学基金联合基金，U2004187，不对称去芳构化环加成反应合成三环嘌呤核苷类化合物，2021/01-2023/12，在研，主持； 2.河南省高校科技创新团队，22IRTSTHN003，核苷类化合物的合成及生物活性，2022/01-2024/12，在研，主持； 3.河南省自然科学基金面上项目，202300410245，嘌呤类化合物的不对称去芳构化环加成反应，2020/09-2022/09，结项，主持；
4.横向项目，5-氟尿嘧啶与尿苷二磷酸生产新工艺的技术开发，2019/08-2023/12，在研，主持； 5. 河南省高校青年骨干教师支持计划，2017GGJS042，嘌呤类化合物的去芳构化反应研究，2018/01-2020/12，结项，主持； 6.省高等学校重点科研项目，18A150007，基于D-A环丙烷的不对称[3+2]环加成反应合成非芳香的嘌呤(核苷)类化合物，2017/01-2019/12，结项，主持； 代表性论文： 20. Dong-Chao Wang,* Jia-Hui Liu, Yu-Qing Guan, and Hai-Ming Guo*, Dearomative [4 + 2] Annulation of Electron-Poor N-Heteroarenes with Azoalkenes for Access to Polycyclic Tetrahydro-1,2,4-triazines. Org. Lett. 2023, 25(19), 3543−3547. 19. Dong-Chao Wang,* Pan-Pan Wu, Pei-Yu Du, Gui-Rong Qu, and Hai-Ming Guo*, Highly Diastereoselective Synthesis of Oxindoles Containing Vicinal Quaternary and Tertiary Stereocenters by a Domino Heck/Decarboxylative Alkynylation Sequence. Org. Lett. 2022, 24(23), 4212-4217. 18. Dong-Chao Wang,* Ting-Ting Yang, Gui-Rong Qu, and Hai-Ming Guo*, Substrate-Dependent Regioselectivity: Pd/PTC Cooperatively Catalyzed Domino Heck/Allylation of Allenamides with α-Carbon of Carbonyl Compounds.J. Org. Chem. 2022, 87(21), 14284-14298. 17. Meng-Cheng Zhang, Dong-Chao Wang,* Hai-Ting Wang, Gui-Rong Qu, and Hai-Ming Guo*, Highly Chemoselective Synthesis of Purino[3,2-c]oxazoles via the Asymmetric Dearomative [3+2] Cycloaddition of Purines with Donor–Acceptor Oxiranes.Org. Lett. 2022, 24(41), 7527-7532. 16. Dong-Chao Wang,* Peng-Peng Cheng, Ting-Ting Yang, Pan-Pan Wu, Gui-Rong Qu,Hai-Ming Guo*, Asymmetric Domino Heck/Dearomatization Reaction of β-Naphthols to Construct Indole–Terpenoid Frameworks. Org. Lett. 2021, 23(20), 7865-7872. (CBG亮点介绍） 15.Zhen Wang, Dong-Chao Wang*,Ming-Sheng Xie, Gui-Rong Qu,Hai-Ming Guo*,Enantioselective Synthesis of Fused Polycyclic Tropanes via Dearomative [3 + 2] Cycloaddition Reactions of 2-Nitrobenzofurans,Org. Lett.2020, 1, 164-167. (CBG亮点介绍 ) 14.Meng-Cheng Zhang, Dong-Chao Wang, Ming-Sheng Xie, Gui-Rong Qu,Hai-Ming Guo,* Shu-Li You,* Cu-catalyzed Asymmetric Dearomative [3 + 2] Cycloaddition Reaction of Benzazoles with Aminocyclopropanes, Chem 2019, 5(1), 156-167.（Highly cited paper, May/2019,WeeChem亮点介绍该工作） 13. Dong-Chao Wang, Ming-Sheng Xie, Hai-Ming Guo*, Gui-Rong Qu, Meng-Cheng Zhang, Shu-Li You*, Enantioselective Dearomative [3+2] Cycloaddition Reactions of Benzothiazoles, Angew. Chem. Int. Ed. 2016, 55, 14111–14115. (highlighted by Synfacts) 12. Zhen Wang, Dong-Chao Wang*, Ming-Sheng Xie, Gui-Rong Qu, Hai-Ming Guo*, Enantioselective Synthesis of Fused Polycyclic Tropanes via Dearomative [3 + 2] Cycloaddition Reactions of 2-Nitrobenzofurans, Org. Lett. 2020, 1, 164-167. 11. Lei Liang, Hong-ying Niu, Dong-Chao Wang*, Xin-he Yang, Gui-Rong Qu, Hai-Ming Guo*, Facile Synthesis of Chiral [2,3]-Fused Hydrobenzofuran via Asymmetric Cu(I)-Catalyzed Dearomative 1,3-Dipolar Cycloaddition, Chem. Commun. 2019, 55, 553-556.（Highly cited paper, July/2019） 10. Xin-He Yang, Jian-Ping Li, Dong-Chao Wang*, Ming-Sheng Xie, Gui-Rong Qu, Hai-Ming Guo*, Enantioselective Dearomative [3+2] Cycloaddition of 2-Nitrobenzofurans with Aldehyde-Derived Morita−Baylis−Hillman Carbonates, Chem. Commun. 2019, 55, 9144-9147. 9. Er-Jun Hao, Dan-Dan Fu, Dong-Chao Wang,* Tao Zhang, Gui-Rong Qu, Gong-Xin Li, Yu Lan,* and Hai-Ming Guo*, Chemoselective Asymmetric Dearomative [3+2] Cycloaddition Reactions of Purines with Aminocyclopropanes, Org. Chem. Front. 2019, 6, 863-867. 8. Man Zhu, Dong-Chao Wang,* Ming-Sheng Xie, Gui-Rong Qu, Hai-Ming Guo,* Enantioselective Friedel-Crafts Alkylation Reactions of β-Naphthols with D-A Aminocyclopropanes, Chem. Eur. J. 2018, 24(58), 15512-15516. 7. Shan-Shan Zhang, Dong-Chao Wang*, Ming-Sheng Xie, Gui-Rong Qu, Hai-Ming Guo*,Highly Chemo- and Diastereoselective Dearomative [3 + 2] Cycloaddition Reactions of Benzazoles with Donor–Acceptor Oxiranes, Org. Lett. 2018, 20(24), 8026–8029. 6. Dong-Chao Wang, Hai-Xia Wang, Er-Jun Hao, Xiao-Han Jiang, Ming-Sheng Xie, Gui-Rong Qu* and Hai-Ming Guo*, Synthesis of 3,3-Disubstituted Oxindoles Containing a 3-(4-Aminobut-2-ynyl) Unit via Domino Heck–Sonogashira Reaction in Water, Adv. Synth. Catal. 2016, 358: 494–499.（as a VIP paper. see Inside cover） 5. Dong-chao Wang, Ran Xia, Ming-sheng Xie, Gui-rong Qu*, Hai-ming Guo*, Synthesis of Cycloalkyl Substituted Purine Nucleosides via a Metal-Free Radical Route, Org. Biomol. Chem. 2016, 14, 4189-4193. (Invited paper ) 4. Dong-Chao Wang, Hong-Ying Niu, Ming-Sheng Xie, Gui-Rong Qu,* Hui-Xuan Wang, and Hai-Ming Guo,*Highly Regioselective Three-Component Domino Heck−Negishi Coupling Reaction for the Functionalization of Purines at C6, Org. Lett. 2014, 16, 262-265. 3. Dong-Chao Wang, Hong-Ying Niu, Gui-Rong Qu, Lei Liang, Xue-Jiao Wei, Yi Jiang, Hai-Ming Guo, Nickel-catalyzed Negishi cross-couplings of 6-chloropurines with organozinc halides at room temperature, Organic & Biomolecular Chemistry 2011, 9, 7663-7666. 2. Dong-Chao Wang, Hai-Ming Guo, Gui-Rong QuEfficient, Green, Solvent-Free Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones via Biginelli Reaction Catalyzed by Cu(NO3)2·3H2O, Synthetic Communications 2010, 40, 1115–1122. 1.DongchaoWang,HongyingNiu,HaimingGuo,XuejiaoWei,RuifangDing,GuirongQu*, Nickel-Catalyzed Negishi Cross-Coupling Reactions of Secondary Alkylzinc Halides with 6-Chloropurines, Chin. J. Org. Chem. 2012, 32, 1072-1076 |