细胞凋亡与动物再生

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摘要:

凋亡是有机体自主程序性死亡方式之一,是生物体正常的生理机能.再生主要指生物体组织或器官在遭受到损伤之后,重建恢复的过程.越来越多的研究表明,细胞凋亡能促进再生程序启动,两者之间存在紧密关系.本文根据动物在演化进程中的地位,阐述了细胞凋亡在低等无脊椎动物、鱼类、有尾两栖类及高等哺乳动物再生过程中的主要成果和最新进展,并总结了细胞凋亡对动物再生可能的作用机制.

Apoptosis is one of the autonomous Programmed death and it is normal physiological function of organisms.Regeneration mainly refers to the process of reconstruction and recovery of a living tissue or organ after it has been damaged.More and more studies have shown that apoptosis can promote the initiation of regeneration process and there is a close relationship between them.Based on the evolution of animals,this paper describes the main achievements and recent advances in the process of apoptosis in lower invertebrates,fish,amphibians and higher mammals,and summarizes the possible effects of apoptosis on animal regeneration mechanism.

作者:

董自梅王静高帅陈广文刘德增

Dong Zimei;Wang Jing;Gao Shuai;Chen Guangwen;Liu Dezeng(College of Life Sciences,Henan Normal University,Xinxiang 453007,China)

机构地区:

betway官方app 生命科学学院

出处:

《betway官方app 学报：自然科学版》 CAS 北大核心 2020年第2期87-93,共7页

基金:

国家自然科学基金(31570376,U1604173,31471965)。

关键词:

细胞凋亡细胞增殖再生

Apoptosis cell proliferation regeneration