开口箭生理活性物质及其药理作用研究进展
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摘要：
开口箭是一种在我国民间具有悠久使用历史的中草药.近年来开口箭的生理活性物质提取和药用价值研发备受关注,开口箭中的甾体类化合物、多糖、挥发油、脂肪酸、金属元素、绿原酸、黄酮类和生物碱类生理活性物质先后被通过不同的方法提取出来,大量实验分析也表明开口箭中的生理活性物质在抗炎、抗菌、抗肿瘤、抗氧化、抗心肌肥厚、抗内毒素及免疫调节等方面具有良好的疗效.但开口箭中部分生理活性物质的提取量仍然较小,提取方法有待改进,且这些活性物质发挥药理作用的机制仍不甚清楚.本文对开口箭的生理活性物质及其药理作用的研究进展予以综述,期望有助于推进开口箭的开发利用.
Tupistra chinensis Bak is a Chinese herbal medicine with long history.In recent years,the extraction of physiological active substances and the development of potential medicinal application for T.Chinensis have attracted considerable attention.Also,some physiological active substances such as steroidal compounds,polysaccharides,volatile oils,fatty acids,metal elements,chlorogenic acids,flavonoids and alkaloids,have been extracted fromT.Chinensis by all kinds of methods.A lot of experimental analysis showed that physiological active substances of T.chinensis had good curative effects on anti-inflammatory,anti-microbial,anti-tumor,anti-oxidation,anti-myocardial hypertrophy,anti-endotoxin and immunomodulatory.However,the extraction capacity of some physiological active substances was still small for the absence of mature extraction methods.Besides,the mechanism of pharmacological activities remained unclear.Thus the paper reviewed the advances of physiological active substances and pharmacological effects of T.Chinensis to serve for the further development and utilization of T.Chinensis.
作者：
唐超智 杨献光 张玉玲 卢浩
机构地区：
betway官方app 生命科学学院
出处：
《betway官方app 学报：自然科学版》 CAS 北大核心 2016年第2期114-118,共5页
基金：
国家自然科学基金(31170733) betway官方app 引进博士科研启动费项目(qd15170)
关键词：
开口箭 生理活性物质 提取方法 药理作用
Tupistra chinensis Bak physiological active substances extraction methods pharmacological effects
分类号：
R282.71 [医药卫生—中药学]
