安乃近的普鲁士蓝分光光度法测定
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摘要:
基于安乃近能将Fe^3＋还原为Fe^2＋,Fe^2＋与铁氰化钾生成可溶性普鲁士蓝,建立了用可见分光光度法间接测定安乃近的新方法.对反应时间和反应温度进行了优化,安乃近浓度在0.06~7.20μg/mL范围内具有良好的线性关系,线性回归方程为A=0.0218＋0.2394 C（μg/mL）,相关系数R=0.999.摩尔吸光系数ε=8.4×10^4 L/（mol·cm）.检测限（3σ/k）为0.024μg/mL.按照本法对市售安乃近片进行了测定,并进行了回收率实验,平均回收率为100.8%,结果令人满意.
Based on our experiments,Fe^3＋ can be reduced into Fe^2＋ by analgin component.The Fe^2＋can further react with K3[Fe（CN）6]to form a soluble compound with Prussian blue.We developed a new method to determine analgin in a drug tablet.After optimization of reaction time and temperature,agood linear relationship was obtained in concentrations of 0.06~7.20μg/mL.A regression equation was obtained as A=0.0218＋0.2394C（μg/mL）.A correlation coefficient of 0.999,an apparent molar absorption coefficient of 8.4×10^4 L/（mol·cm）,and a detection limit of 0.024μg/mL were obtained.An average recovery of 100.8% was achieved.Finally,we quantitatively determined the analgin in several drug tablets,and the result is satisfied.
作者:
刘荣森 张长水
机构地区:
河南林业职业学院 河南科技大学化工与制药学院
出处:
《betway官方app 学报：自然科学版》 CAS 北大核心 2015年第2期94-97,共4页
基金：
国家自然科学基金(1105130)
关键词：
安乃近 普鲁士蓝 分光光度法
analgin Prussian blue spectrophotometry
分类号:
O657.32 [理学—分析化学]
