一、个人简介
主要从事水产动物内分泌及代谢和水产动物肠道益生菌研究,对功能基因进行发掘,研究其对水产动物生长、糖脂代谢、免疫的调控机制。近五年来主持国家自然科学基金、河南省自然科学基金、河南省科技攻关项目等5项,在《Frontiers inImmunology》、《Aquaculture》等SCI期刊及国内重要期刊发表及参与发表学术论文50余篇,授权发明专利2项。
二、通讯地址
地址:河南省新乡市牧野区建设东路46号
E-mail: ygk5210207@126.com
电话:15090322075
三、教育背景
博士(2012/09-2017/12):中山大学,生命科学学院,水生生物学专业
学士(2008/09-2012/06):佳木斯大学,生命科学学院,生物技术专业
四、工作经历
2018/03-至今:betway官方app 水产学院,讲师
五、承担课程
生物化学、分子营养学、水产动物营养与饲料实验
六、研究方向
1.水产动物内分泌及代谢
2.益生菌功能基因的发掘及应用
七、科教项目
1)胰岛素对草鱼肝脏糖稳态的调控研究,河南省科技攻关项目(192102110193)
2)GIP/GIPR调控草鱼脂肪代谢的研究,河南省科技攻关项目(202102110259)
3)Irisin对鲤肝脏糖脂代谢的调控机制研究,河南省高等学校重点科研项目(20A240005)
4)GIP/GIPR对草鱼脂肪沉积的调控机制研究,河南省自然科学基金(212300410174)
5)Amuc_1100介导TLR2/c-Jun/GIP通路调控大口黑鲈糖代谢机制研究,国家自然科学基金青年项目(32303020)
八、代表性研究成果(发表论文 出版刊物 授权专利)
1)Guokun Yang, Aixia Jiang, Huimin Cai, Fu You, Shengkui Wu, Yanmin Zhang, Xindang Zhang,Yawei Shen, Xulu Chang, Wenpan Hu, Keke Li, Xiaolin Meng*. Supplementation withAkkermansiamuciniphilaimproved glucose metabolism disorder in common carp (Cyprinus carpioL.),Aquaculture, 2023, 2023: 739465.
2)Guokun Yang, Xiaomin Liang, Shuangyang Xu, Huimin Cai, Limei Ma, Xulu Chang, Yanmin Zhang, Liping Yang, Xiaolin Meng*. Molecular identification of Igf3 and its roles in grass carp (Ctenopharyngodon idella). Aquaculture 2022, 548.
3)Guokun Yang, Xiaomin Liang, Chaobin Qin, Liping Yang, Yanmin Zhang, Ronghua Lu, Xiao Yan, Xiaolin Meng, Guoxing Nie*. Molecular cloning, tissue distribution and functional characterization of glucose-dependent insulinotropic peptide (GIP) gene inCtenopharyngodon idella. Aquaculture 2022, 548.
4)Guokun Yang, Xiaomin Liang, Yanle Jiang, Chengquan Li, Yanmin Zhang, Xindang Zhang, XuluChang, Yawei Shen, Xiaolin Meng*. Molecular Characterization of Grass Carp GIPR and Effect ofNutrition States, Insulin, and Glucagon on Its Expression, Aquaculture Nutrition, 2022, 2022:4330251.
5)Guokun Yang, Xiaomin Liang, Yanle Jiang, Chengquan Li, Jihong Hu, Yanmin Zhang, XindangZhang, Xulu Chang, Wenpan Hu, Keke Li, Xiaolin Meng*. Myonectin in grass carp (Ctenopharyngodonidella): Molecular cloning and effect of nutrition state, insulin and glucagon on myonectinexpression, Aquaculture Reports, 2022, 26(2022): 101306.
6)Guokun Yang, Xiaomin Liang, Jihong Hu, Chengquan Li, Wenpan Hu, Keke Li, Xulu Chang, Yanmin Zhang, Xindang Zhang, Yawei Shen, Xiaolin Meng*. Feeding tea polysaccharides affects lipid metabolism, antioxidant capacity and immunity of common carp (Cyprinus carpioL.), Frontiers in Immunology, 2022, 13: 1074198.
7)Guokun Yang, Wenli Zhao, Chaobin Qin, Liping Yang, Xiaolin Meng,Ronghua Lu, Xiao Yan, Xianglin Cao, Yanmin Zhang, Guoxing Nie*. Molecularidentification of grass carpigfbp2and the effect of glucose, insulin, and glucagon onigfbp2mRNA expression, Fish Physiology and Biochemistry 2020, 46: 1469-1482.
8)Guokun Yang,Wenli Zhao, Chaobin Qin, Liping Yang, Xiaolin Meng,Ronghua Lu, Xiao Yan, Xianglin Cao, Yanmin Zhang, Guoxing Nie*, Igfbp3 in grasscarp (Ctenopharyngodon idellus): Molecular identification and mRNA expressionunder glucose, insulin and glucagon, Comparative biochemistry and physiology.Part B, Biochemistry & molecular biology, 2020, 242: 110394.
9)Guokun Yang,Beichen Chen, Caiyun Sun, Xi Yuan, Yazhou Zhang, JingkaiQin, Wensheng Li*, Molecular identification of grouper Igfbp1 and itsmRNAexpression in primary hepatocytes under Gh and insulin, General and ComparativeEndocrinology, 2019, 281: 137-144.
10)Guokun Yang, Qinqin Song, Caiyun Sun, Jingkai Qin, Jirong Jia, Xi Yuan, Yazhou Zhang, Wensheng Li*. Ctrp9 and adiponectin receptors in Nile tilapia (Oreochromis niloticus): Molecular cloning, tissue distribution and effects on reproductive genes, General and Comparative Endocrinology, 2018, 265: 160-173.
11)GuokunYang,Chaobin Qin, Bin Wang, Jirong Jia, Xi Yuan,Caiyun Sun, Wensheng Li*.Molecular identification and functional analysis of CTRP9 inEpinephelus coioides. Journal of Molecular Endocrinology, 2017, 58(4): 179-191.
12)李文笙,杨国坤,秦超彬,斜带石斑鱼ctrp9基因、编码蛋白及其应用,2016.06.15,中国, ZL201410380895.6
13)李文笙,杨国坤,斜带石斑鱼insulin基因、编码蛋白及其应用, 2021.07.27,中国, ZL201711001284.6