柴国利,女,博士,硕士生导师,讲师
联系方式:guolichai@126.com
教育经历:
2014/09-2017/12 中国科学院上海有机化学研究所 有机化学 理学博士 导师:黄乃正
2011/09-2014/07 大连理工大学 应用化学 工学硕士
2007/09-2011/07 信阳师范学院 化学 理学学士
工作经历:
2023-06至今 betway官方app 抗病毒性传染病创新药物全国重点实验室 讲师
2018-01至2023-05 betway官方app 化学化工学院 讲师
研究领域与兴趣:
1.功能有机分子的设计与合成
2.不对称催化
近年来主持的主要科研项目:
1.河南省自然科学基金-青年科学基金项目(232300421371, 2023.01-2024.12)
2.河南省高等学校重点科研项目(21A150028, 2021.01-2022.12)
3.betway官方app 国家级科研项目培育基金-青年培育(2020PL20, 2020.01-2022.12)
4.betway官方app 博士科研启动课题(qd18005, 2019.01-2021.09)
代表性论文:
(12)Guo-Li Chai,*#Xiao Wang,# Ya-Jing Hou, Wen-Hui, Ren, Junbiao Chang.* Chiral-Boron-Complex Catalyzed Asymmetric Inverse-Electron-Demand Aza-Diels−Alder Reaction of βTrifluoromethyl α,β-Unsaturated Ketones with Cyclic NSulfonyl Ketimines.Org. Lett.2023,25(38), 6982–6986.
(11).Xiao Wang,Guo-Li Chai,*Ya-Jing Hou, Ming-Qian Zhou, Junbiao Chang.* Enantioselective Synthesis of Chiral Organosilicon Compounds by Organocatalytic Asymmetric Conjugate Addition of Boronic Acids to βSilyl-α,β-Unsaturated Ketones.J. Org. Chem.2023, 88(5), 3254–3265.
(10)Guo-Li Chai,*#En-Ze Yao,# Rui-Hao Liu, Junbiao Chang.* Chiral-Boron-Complex-Catalyzed Asymmetric [3 + 2] Cycloaddition of 2′-Hydroxychalcones withN,N′Cyclic Azomethine Imines.Org. Lett.2022,24(35), 6449–6454.
(9)Guo-Li Chai,*Ping Zhang, En-Ze Yao, Junbiao Chang.*Enantioselective Conjugate Addition of Boronic Acids to α,β-Unsaturated 2-Acyl Imidazoles Catalyzed by Chiral Diols.J. Org. Chem.2022, 87(14), 9197–9209.
(8) En-Ze Yao,Guo-Li Chai,*Ping Zhang, Bo Zhu, Junbiao Chang.*Chiral dihydroxytetraphenylene-catalyzed enantioselective conjugate addition of boronic acids to β-enaminones.Org. Chem. Front.2022,9(9), 2375–2381.
(7) Lu Zhao,#En-Ze Yao,#Guo-Li Chai,*Shi-Yu Ma, Junbiao Chang.*Organocatalyzed Enantioselective Conjugate Addition of Boronic Acids to β,γ-Unsaturated α-Ketoesters.J. Org. Chem.2021,86(24), 18211–18223.
(6) Ping Zhang,Guo-Li Chai,* En-Ze Yao, Li-Xiao Guo, Xue-Yu Liu, Junbiao Chang.*Asymmetric Double-Conjugate Addition of Alkenylboronic Acids to Dienones Catalyzed by Chiral Diols.Org. Chem. Front.2021,8(7), 1575–1580.
(5)Guo-Li Chai,* Yan Qiao, Ping Zhang, Rong Guo, Juan Wang, Junbiao Chang.*Chiral Hydroxytetraphenylene-Boron Complex-Catalyzed Asymmetric Diels-Alder Cycloaddition of 2'-Hydroxychalcones.Org. Lett.2020,22(20), 8023–8027.
(4)Guo-Li Chai,* A-Qiang Sun, Dong Zhai, Juan Wang, Wei-Qiao Deng, Henry N. C. Wong, Junbiao Chang. Chiral Hydroxytetraphenylene-Catalyzed Asymmetric Conjugate Addition of Boronic Acids to Enones.Org. Lett.2019,21(13), 5040–5045.
(3)Guo-Li Chai, Bo Zhu, Junbiao Chang.* Synthesis and Application of Substituted 1,16-Dihydroxytetraphenylenes in Catalytic Asymmetric Allylboration of Ketones.J. Org. Chem.2019,84(1), 120–127.
(2)Guo-Li Chai, Jian-Wei Han, Henry N. C. Wong.*Asymmetric Darzens Reaction of Isatins with Diazoacetamides Catalyzed by Chiral BINOL-Titanium Complex.J. Org. Chem.2017,82(23), 12647–12654.
(1)Guo-Li Chai, Jian-Wei Han, Henry N. C. Wong.* Hydroxytetraphenylenes as Chiral Ligands: Application to Asymmetric Darzens Reaction of Diazoacetamide with Aldehydes.Synthesis2017,49(1), 181–187.